Gah, my mistake on the book title. Was too excited about potential ramifications when posting.
Dunno about disregarding the danger posed by a well-built spider drive ship though. If it was me, I'd build the spider-SD with a couple hudred torpedo-sized spider-escorts loaded with point defense. Any drones get close enough would get shot by PDLCs or countermissiles that wouldn't even come from the main ship so you couldn't localize it from them. And if the worst happens and the spider-SD has to duke it out with normal SDs, it shuts down its drive, raises bubble sidewall, locks onto the torps with tractors exactly the same way normal-SD locks on to its keyholes, and fights on even footing.
It might lack the wedge's protection and huge acceleration but has an even stronger sidewall, more broadside surface, no wedge interference for sensors and control links, can't be locked onto from further than a couple million clicks at best and lacks the vulnerable unarmored alpha rings of normal SDs.
And that's without any of the tricks the Alignment could have developed that we don't know about.