ldwechsler wrote:quite possibly a cat wrote:Naturally becoming a separate species would be hard to do in a reasonable time frame, if you have a reasonably large population.
Unnaturally creating a new species could be as easy as pasting a couple chromosomes together and rearranging some of the DNA. You wouldn't even need to make new genes!
Actually, I would think the biggest area for potential "speciation" would be creating two mutually incompatible gene mods. Even if both lines can interbreed with classic humans, they might not be able to interbreed with each other.
From what we've seen here on earth, speciation is difficult. Lots of breeds of horses, dogs, etc., and they breed. To not breed, you would need either some sort of genetic "instruction" or a real change in genetic form.
I think Eric pushed things a bit. Note also that there seems not be be a problem with people on San Martin breeding (never mentioned anywhere in text) and they've been under extreme gravity. Honor is a Meyerdahl B and she has been able to breed with Hamish who is not.
Breeding animals is relatively "natural". Natural changes take a long time for specialization.
However if you are making arbitrary changes with gene altering technologies you can get a different species really easily. So one genetic "problem" that people can have is chromosomes with some of the DNA sections reversed. The person who has the section of DNA flipped around can be totally fine.
An inversion. You can also swap chunks of DNA around in a
balanced translocation. There are a couple ways this can cause problems. First, it might break a gene or regulatory component, but that's not all that common. The second area where it can cause problems is during gamete production. If the change is in only one of chromosomes (heterogeneous) of a pair you might have unbalanced chromosomes after gamete production in the gametes! That means lowered fertility, or even infertility.
However a genetic engineer could do that a bunch of times to both chromosomes (homogeneous) and make sure not to break anything! Then the person wouldn't have any problems and their gametes would be fine! However, if they had a child with an unaltered human, that child would have a whole crapton of heterogeneous chromosomes. They'd be infertile.
BAM! Technically you have a new species, if you go by the interbreeding definition. But outwardly? Exactly like a regular human.
The point is, if you want to deliberately create a new species, you can. In Honorverse it seems like they try to make sure mods actually result in someone who is human.
That said: I'm not sure how the Mfecanes could be a couple generations away from being a new species. A couple of generations shouldn't make much of a change. It might be the character who said it was just wrong and doesn't understand what they're talking about!